Routinely evaluate patients, specifically when initiating and titrating dose and when given concomitantly with other drugs that depress respiration; alternatively, consider utilization of non-opioid analgesics in these patients

butorphanol decreases effects of fentanyl by pharmacodynamic antagonism. Steer clear of or Use Alternate Drug. Coadministration of mixed agonist/antagonist and partial agonist opioid analgesics may perhaps decrease fentanyl's analgesic effect And perhaps precipitate withdrawal symptoms.

lonapegsomatropin will decrease the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

If coadministration of CYP3A4 inhibitors with fentanyl is necessary, check patients for respiratory depression and sedation at Repeated intervals and consider fentanyl dose adjustments right until stable drug effects are accomplished.

If coadministration of CYP3A4 inhibitors with fentanyl is important, check patients for respiratory depression and sedation at Repeated intervals and consider fentanyl dose adjustments until eventually stable drug effects are obtained.

lenacapavir will boost the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

This is much more likely to come about from initiation of elranatamab move-up dosing around fourteen times after the first treatment dose and during and after CRS.

buprenorphine decreases effects of fentanyl by pharmacodynamic antagonism. Steer clear of or Use Alternate Drug. Coadministration of mixed agonist/antagonist and partial agonist opioid analgesics may perhaps lower fentanyl's analgesic effect And perhaps precipitate withdrawal symptoms.

fentanyl intranasal and fentanyl both equally boost sedation. Stay away from or Use Alternate Drug. Restrict use to patients for whom substitute treatment options are insufficient

danazol will improve the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

fentanyl, clemastine. Both increases toxicity of the other by pharmacodynamic synergism. Modify Therapy/Observe Carefully. Coadministration of fentanyl with anticholinergics might maximize risk for urinary retention and/or significant constipation, which may cause paralytic ileus.

Use in patients with acute or serious bronchial asthma within an unmonitored placing or in absence of resuscitative products fentanyl z czego powstaje is contraindicated

Modify Therapy/Check Intently. Keep an eye on for respiratory depression and sedation at frequent intervals and consider fentanyl dose changes until finally stable drug effects are accomplished.

Observe Closely (1)trofinetide will improve the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism.